AgenTus (Lexington, MA) is seeking a creative and innovative Scientist/Sr. Scientist to join the Molecular Biology group. The successful candidate will work as part of an integrated, cross-site team to craft materials and processes that enable the validation of optimal targeting molecules (CARs and TCRs) for cellular therapeutics. Come join our small team and work at an exciting start-up in the field of adoptive cell therapy!
The successful candidate will work as part of a core team to create and characterize targeting molecules, including TCRs and CARs, that will enable the development of novel cellular therapeutics. The candidate will be expected to work independently and as part of a cross-functional group to design, engineer and generate DNA constructs, viral vectors and other gene delivery methods. We are looking for an innovative thinker to develop and optimize higher-throughput processes for cloning and functionally testing the biological activity of new molecules in primary human cells. Work will include plasmid design and construction, molecular engineering, retro/lentiviral vector production and cell-based immunologic assays. The candidate should have the ability to independently troubleshoot technical issues and develop optimized processes for critical tasks. This position has the potential to lead a team of 1-2 research associates.