• Analyst - Bioinformatics

    Job Locations US-MA-Lexington
    Job ID
  • Overview

    The Agenus computational biology group is seeking a highly talented and motivated data analyst to contribute to the team’s efforts in learning from large-scale datasets to facilitate the characterizing of immunotherapeutic drug candidates and biomarkers. The successful candidate will use his/her coding and scripting skills for improving existing and creating novel bioinformatics pipelines for the processing, analysis, and interpretation of next generation sequencing and functional genomics datasets. He/she will develop and maintain databases and web interfaces and contribute to the team’s efforts for data storage and curation from internal and external sources.


    - Informatics operations and data analysis:
    o Build robust informatics pipelines for analyzing sequencing data and help establishing the computational infrastructure required
    o Use existing software for diverse tasks including: sequence alignment, transcriptome analysis, variant calling, inter-sample comparison, algorithm evaluation, data management, and data retrieval
    o Incorporate software into specialized analysis workflows
    o In collaboration with drug discovery project teams develop data analysis plans and use web-based bioinformatics tools as well as public and proprietary databases to facilitate interpretation of data
    o Use best practices to document your work and the flow of samples and information for projects
    o Generate reports and visualizations for deliverables, presentations, and publications
    - Project management and communication:
    o Review, analyze, and evaluate systems and user needs, also in the contexts of existing tools and applicability
    o Participates in various aspects of the software development life cycle: identification of key requirements, design, code generation, testing, implementation, and documentation
    o Appropriately and effectively communicate project statuses and utilize project and time management skills to complete projects within specified timelines


    The candidate is expected to hold a master's degree in bioinformatics or computer sciences, or a relevant bachelor's degree with at least 2 years related experience. We are seeking candidates with:
    - Strong experience using at least on scripting programming language (Python/Perl)
    - Experience with R is desired
    - Experience with relational databases (MySQL and/or Oracle) and client-server concepts
    - Experience working with Linux and Windows operating systems
    - Knowledge of parallel computing in local and cloud environments (preferably AWS)
    - Experience with next generation sequencing platforms, data formats, and analysis pipelines is preferred
    - Willingness to closely collaborate with bench scientist and understand the biological concepts behind the scientific questions
    - Strong analytical and problem-solving skills
    - Excellent verbal and written communication skills


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