Research Associate or Senior Research Associate

Job ID


The Agenus Immuno-modulatory Drug Discovery group (Lexington, MA) is seeking a highly talented and motivated research associate to contribute to the team's efforts of characterizing immunotherapeutic drug candidates aiming to advance research stage programs into early clinical development.

The successful candidate will have primary responsibilities for the design, execution, and analysis of immunology-based assays, including functional assays based on flow cytometry and microscopy using primary immune cell cultures. He/she will provide clear and concise data summaries for technical reports, laboratory protocols, and presentations. The position offers the successful candidate exciting opportunities to develop skills and gain expertise in immuno-oncology as part of an innovative and collaborative team committed to discover, develop, and deliver novel medicines for the treatment of cancer.


  • Perform cell-based phenotyping and functional assays designed to characterize the efficacy of drug candidates
  • Propose, evaluate, and troubleshoot novel assays, methodologies, and technologies needed to establish mechanisms of action for drug candidates in different immune cell subsets
  • Maintain and expand sensitive primary immune cell cultures and optimize culture conditions
  • Design and optimize antibody panels for flow cytometric phenotyping of immune cell subsets
  • Careful plan and execute experimental work in an organized manner within agreed timelines, while maintaining clear and accurate research documentation
  • Communicate relevant progress in assay development within the team and across functions


The candidate is expected to have a degree in immunology, cancer biology or a related field. For a Research Associate position a BS or MS degree with related laboratory experience is required. For a Senior Research Associate position a MS or PhD degree with a minimum of 3-7 years or 2-4 years of experience, respectively, is required. We are seeking candidates that have:

  • Strong expertise with tissue culture procedures, including isolation, culture and differentiation of primary immune cells,
  • Experience in designing multi-color antibody panels and performing flow cytometry-based phenotyping of cells,
  • Experience in designing and performing immunology-based assays,
  • Experience with microscopy-based assays is a plus,
  • Basic knowledge of molecular biology and biochemical methodologies,
  • Strong written and verbal communication skills for preparing and delivering oral presentations, technical documents, and project report summaries.


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