Agenus

  • Senior Research Associate

    Job Locations US-MA-Lexington
    Job ID
    2017-1312
    Category
    Research
  • Overview

    • As part of a team, this person will be supporting in vivo studies and analyzing samples obtained from these studies.
    • Responsible for conducting and managing in vivo studies to determine the efficacy of both small molecule and biotherapeutic approaches.
    • The evaluation and development of new technologies, biomarkers and in vivo models are key components of this position.
    • Any background and knowledge in immunology is a plus for this position.
    • Plan and conduct of experiments in vivo studies in support of Inflammation & Immunology therapeutic portfolio
    • Formulation of compounds and administration of drugs and experimental compounds by various routes
    • Collection of blood and various tissues
    • Ability to learn and conduct other animal-related techniques
    • Ex vivo analysis of animal samples
    • Maintain well-organized records and documentation
    • Data entry and analysis

    Qualifications

    • M.Sc. or B.Sc. degree in biology, pharmacology, Immunology or related biological science
    • B.Sc. degree with 6 years or M.Sc. degree with 5 years' experience
    • Experience working with small laboratory animals, preferably in a biotech or pharmaceutical environment
    • Well established hands-on experience with rodent in vivo dosing and handling techniques
    • Understanding of cancer biology
    • Experience with animal models of cancer is desirable
    • Good organizational and communication skills, ability to focus attention to details
    • A high degree of flexibility, and a willingness and ability to work as a team member
    • Weekend or after hours work may be required
    • Technical expectations
    • Design and conduct experiments to support the mechanistic and disease biomarker discovery for in vivo models
    • Planning, coordination and execution of in vivo and ex vivo pharmacology studies in rodent models
    • Experience with small animal handling procedures, injections, oral dosing
    • Experience in tissue dissection and tissue preparation for histology, RNA, and protein analysis
    • Experience in molecular biology techniques such as ELISA, MSD, FACS, TLDA and RT-PCR, CBA and Luminex assays

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