- As part of a team, this person will be supporting in vivo studies and analyzing samples obtained from these studies.
- Responsible for conducting and managing in vivo studies to determine the efficacy of both small molecule and biotherapeutic approaches.
- The evaluation and development of new technologies, biomarkers and in vivo models are key components of this position.
- Any background and knowledge in immunology is a plus for this position.
- Plan and conduct of experiments in vivo studies in support of Inflammation & Immunology therapeutic portfolio
- Formulation of compounds and administration of drugs and experimental compounds by various routes
- Collection of blood and various tissues
- Ability to learn and conduct other animal-related techniques
- Ex vivo analysis of animal samples
- Maintain well-organized records and documentation
- Data entry and analysis
- M.Sc. or B.Sc. degree in biology, pharmacology, Immunology or related biological science
- B.Sc. degree with 6 years or M.Sc. degree with 5 years' experience
- Experience working with small laboratory animals, preferably in a biotech or pharmaceutical environment
- Well established hands-on experience with rodent in vivo dosing and handling techniques
- Understanding of cancer biology
- Experience with animal models of cancer is desirable
- Good organizational and communication skills, ability to focus attention to details
- A high degree of flexibility, and a willingness and ability to work as a team member
- Weekend or after hours work may be required
- Technical expectations
- Design and conduct experiments to support the mechanistic and disease biomarker discovery for in vivo models
- Planning, coordination and execution of in vivo and ex vivo pharmacology studies in rodent models
- Experience with small animal handling procedures, injections, oral dosing
- Experience in tissue dissection and tissue preparation for histology, RNA, and protein analysis
- Experience in molecular biology techniques such as ELISA, MSD, FACS, TLDA and RT-PCR, CBA and Luminex assays
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