Agenus

Scientist

US-MA-Lexington
Job ID
2017-1312
Category
Research

Overview

  • As part of a team, this person will be supporting in vivo studies and analyzing samples obtained from these studies.
  • Responsible for conducting and managing in vivo studies to determine the efficacy of both small molecule and biotherapeutic approaches.
  • The evaluation and development of new technologies, biomarkers and in vivo models are key components of this position.
  • Any background and knowledge in immunology is a plus for this position.
  • Plan and conduct of experiments in vivo studies in support of Inflammation & Immunology therapeutic portfolio
  • Formulation of compounds and administration of drugs and experimental compounds by various routes
  • Collection of blood and various tissues
  • Ability to learn and conduct other animal-related techniques
  • Ex vivo analysis of animal samples
  • Maintain well-organized records and documentation
  • Data entry and analysis

Qualifications

  • M.Sc. or B.Sc. degree in biology, pharmacology, Immunology or related biological science
  • B.Sc. degree with 6 years or M.Sc. degree with 5 years' experience
  • Experience working with small laboratory animals, preferably in a biotech or pharmaceutical environment
  • Well established hands-on experience with rodent in vivo dosing and handling techniques
  • Understanding of cancer biology
  • Experience with animal models of cancer is desirable
  • Good organizational and communication skills, ability to focus attention to details
  • A high degree of flexibility, and a willingness and ability to work as a team member
  • Weekend or after hours work may be required
  • Technical expectations
  • Design and conduct experiments to support the mechanistic and disease biomarker discovery for in vivo models
  • Planning, coordination and execution of in vivo and ex vivo pharmacology studies in rodent models
  • Experience with small animal handling procedures, injections, oral dosing
  • Experience in tissue dissection and tissue preparation for histology, RNA, and protein analysis
  • Experience in molecular biology techniques such as ELISA, MSD, FACS, TLDA and RT-PCR, CBA and Luminex assays

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