Scientist II

Job ID


We are seeking a highly motivated Scientist to join the Vaccine Research group (Cancer Immunology) at Agenus, Lexington, MA. A strong background in vaccine research in oncology or infectious disease as evidenced by peer reviewed publications is required for this position. The successful candidate will be responsible for evaluation of both personalized and non-personalized synthetic/recombinant, cancer vaccine candidates in animal models as stand-alone therapeutics and in combination with other immune modulating agents. Evaluation of the company’s existing adjuvants and exploration of other adjuvants will be an important component of this research. He/she will be expected to work independently, and to design, execute and interpret experiments in the collaborative global research environment at Agenus. He/she would be tasked with developing this research into novel therapeutic hypotheses, with an expectation that novel findings will be published in impactful journals.





  • Design and execute research plans to discover and validate novel therapeutic concepts in the areas of cancer immunotherapy
  • Contribute in the development and implementation of the cancer immunology research strategy at Agenus
  • Evaluate immune readouts (PD endpoints) that can be incorporated in an early clinical development setting
  • Represent Agenus as the scientific lead for research projects internally, and with external partners
  • Provide input on IND/NDA/BLA preparation activities.
  • Set up collaborations with academic partners and interface with study investigators, scientific and corporate partners
  • Facilitate productive research interactions across groups at Agenus
  • Demonstrate excellent communication skills (interpersonal and in group forums)
  • Mentor and lead research associates, scientists and postdoctoral fellows, as required



A PhD or PhD/MD and post-doctoral training in molecular immunology, molecular oncology cancer immunology or infectious disease models is required. A minimum of 3-5 years of research experience with demonstrated academic/industry achievement, as evidenced by publications in high impact journals, is required. Experience with murine disease models and related immune monitoring assays are required skills. Candidates should have excellent communication skills, be able to distill complex ideas and articulate innovative solutions, and be dedicated to translating basic translational research insights into impactful human therapies.


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